Reliability of finger stick capillary blood for the lymphocyte micronucleus assay
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چکیده
منابع مشابه
Finger-stick blood sampling methodology for the determination of exercise-induced lymphocyte apoptosis.
Exercise is a physiological stimulus capable of inducing apoptosis in immune cells. To date, various limitations have been identified with the measurement of this phenomenon, particularly relating to the amount of time required to isolate and treat a blood sample prior to the assessment of cell death. Because of this, it is difficult to determine whether reported increases in immune cell apopto...
متن کاملMicronucleus assay of human lymphocytes: a comparison of cytokinesis-block and human capillary blood lymphocytes methods.
Micronucleus (MN) expression in Peripheral blood lymphocytes is well established as a method to monitor chromosome damage in human populations. The use of MN as a measure of chromosome damage in peripheral blood lymphocytes was first proposed by Countryman and Heddle and subsequently improved with the development of the cytokinesis-block micronucleus (CBMN) method, which has been extensively us...
متن کاملEvaluation of the Xpert HCV Viral Load point-of-care assay from venepuncture-collected and finger-stick capillary whole-blood samples: a cohort study.
BACKGROUND Point-of-care hepatitis C virus (HCV) RNA testing offers an advantage over antibody testing (which only indicates previous exposure), enabling diagnosis of active infection in a single visit. In this study, we evaluated the performance of the Xpert HCV Viral Load assay with venepuncture and finger-stick capillary whole-blood samples. METHODS Plasma and finger-stick capillary whole-...
متن کاملThe use of the lymphocyte cytokinesis-block micronucleus assay for monitoring pesticide-exposed populations.
Pesticides are widely used around the world, and hundreds of millions of people are exposed annually in occupational and environmental settings. Numerous studies have demonstrated relationships between pesticide exposure and increased risk of cancers, neurodegenerative and neurodevelopmental disorders, respiratory diseases and diabetes. Assessment of genotoxicity of pesticides and biomonitoring...
متن کاملFinger-Stick Glucose Monitoring
S ince its introduction three decades ago, self-monitoring of blood glucose (SMBG) using finger-stick blood samples, test strips, and portable meters has aided diabetes management, principally by enabling patients— particularly those treated with insulin—to become full partners along with health professionals in striving for excellent glycemic control. Over time the use of glucose meters has be...
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ژورنال
عنوان ژورنال: Mutagenesis
سال: 1997
ISSN: 0267-8357,1464-3804
DOI: 10.1093/mutage/12.2.79